WASHINGTON(AP)
Don't be surprised if your doctor orders a vitamin D test
during your next physical. Blood tests to check levels of the
so-called sunshine vitamin are on the rise as doctors and patients
react to headline-grabbing research that suggests having too little
may not only hurt your bones _ it might increase your risk of
certain cancers or heart disease.
But there are problems with deciding next steps: As intriguing
as the research is, it's far from proof that vitamin D really
is that powerful. Also, it's not clear just how much is enough
_ and megadoses can harm.
Nor are there guidelines on exactly who should be tested, or
how. Test during winter, for example, and in much of the country
people will harbor considerably less vitamin D than if they were
tested in the sunny summer.
Still, "the hope is so high that it will have some effect
that everybody's asking for it," says Dr. Clifford Rosen
of the Maine Medical Center, who is helping government researchers
evaluate the research. "It's pretty much the wild, wild
West right now."
There is no count of how many people get their vitamin D
checked. But at testing giant LabCorp, the volume of vitamin D
tests doctors order has, on average, doubled every year for the
past four, says spokesman Eric Lindblom. So far this year, test
orders are up another 90 percent. At competitor Quest Diagnostics,
the volume of D tests approximately tripled between May 2006 and
last May.
Dr. James Underberg, a New York University internist, once
checked vitamin D levels mostly in people at risk of thinning
bones. Over the past year, he's begun screening more patients,
especially those at risk of heart disease, as he closely watches
the evolving research.
"We don't have any data yet that says taking an
otherwise healthy adult who's vitamin D deficient and
supplementing them prevents cancer, reduces the risk of heart
disease," Underberg acknowledges.
"You just have to keep your eyes and ears open to make sure
something doesn't show up counterintuitive to what people
thought," he adds, noting that other once-touted heart
protections _ estrogen therapy after menopause, for example _
failed when more rigorously researched.
Dr. Ann Marie Gordon, a Washington, D.C., internist, isn't
hesitating. She has made a vitamin D test a routine part of every
physical, and she estimates that 60 percent of her patients are
low.
"Any kind of deficiency needs to be addressed. Whether
patients are convinced or the medical world is convinced that
vitamin D goes beyond bones is irrelevant," she says.
Vitamin D and calcium go hand in hand. You need a lifetime of
both to build strong bones. We get D in three ways: sun exposure,
dietary supplements or certain foods, particularly D-fortified
milk, orange juice and cereals.
Scientists have been interested in vitamin D's possibly
broader effects for decades, since noticing that cancer rates
between similar groups of people were lower in sunny southern
latitudes than in northern ones. In recent years, studies have
linked low levels of vitamin D with breast, prostate and colon
cancer, heart disease, diabetes and certain other ailments _ as
well as an overall increased risk of death.
Much of the evidence is circumstantial. There's a
chicken-or-egg question: Does correlating how much vitamin D is in
someone's blood at a certain time really mean it triggered or
worsened a disease _ or did the disease, or other risk factors,
trigger the low vitamin D? Being a couch potato, for instance, is a
key risk for heart disease, and also keeps you out of the sun.
Moreover, not all vitamin D studies find that the nutrient
helps. The disappointing ones seldom make headlines.
But the increasing interest in vitamin D parallels increasing
concern that people aren't getting enough _ and increasing
confusion about how much that might be.
Currently, the government and other health authorities recommend
consuming anywhere from 200 to 600 international units a day from
food or supplements, depending on your age _ levels that many
vitamin D proponents say are too low.
There's no consensus on how to balance the risk of skin
cancer from sun exposure with vitamin D needs. Some specialists
recommend 10 to 15 minutes daily without sunscreen. Others say
sunscreen doesn't completely block vitamin D production so
sunscreen users will get enough. Regardless, time of day, season
and geography play a role.
There's not even good agreement on what's a low level _
different studies use different definitions, notes a newly
published research review sponsored by the National Institutes of
Health.
The government has begun discussions with the Institute of
Medicine to determine if the daily recommended intake needs
changing.
Meanwhile, because megadoses may be toxic, the government
considers 2,000 IUs a day the upper limit, although doctors may
recommend 10,000 or even 50,000 IUs for a short period if someone
needs a rapid boost.
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EDITOR'S NOTE _ Lauran Neergaard covers health and medical
issues for The Associated Press in Washington.
Copyright 2008 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.